Antihistamines in children and adolescents: A practical update
Allergol. immunopatol
; 48(6): 753-762, nov.-dic. 2020. tab
Artigo
em Inglês
| IBECS
| ID: ibc-199267
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Histamine is a chemical mediator, released predominantly by tissue mast cells, circulating basophils, and neurons, which are activated in response to various immunological and non-immunological stimuli. Histamine has to bind to specific receptors to exert its physiological and pathophysiological functions. Endogenous histamine is the main mediator of the immediate allergic response, which moreover, performs other multiple functions, including regulation of gastric secretion, neurotransmission in the central nervous system, and immunomodulatory activity. The involvement of histamine in various disorders and the importance of receptors in the clinical features have relevant implications in clinical practice. Anti-H1 antihistamines contrast the histamine-dependent effects, mainly concerning nasal symptoms and cutaneous itching and wheal. Antihistamines are among the most prescribed drugs in pediatric care. This review updates the practical use of antihistamines in children and adolescents
RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Antagonistas dos Receptores Histamínicos
Limite:
Adolescente
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2020
Tipo de documento:
Artigo
Instituição/País de afiliação:
Casa di Cura Villa Montallegro/Italy
/
University of Campania "Luigi Vanvitelli"/Italy
/
University of Catania/Italy
/
University of Messina/Italy
/
University of Pavia/Italy
/
University of Pisa/Italy