Circulating exosomal miRNAs and cancer early diagnosis
Clin. transl. oncol. (Print)
; 24(3): 393-406, marzo 2022.
Article
em En
| IBECS
| ID: ibc-203537
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Microribonucleic acids (miRNAs) are small non-coding ribonucleic acids (ncRNAs), which can affect recognition of homologous sequences and interfere with transcription. It plays key roles in the initiation, development, resistance, metastasis or recurrence of cancers. Identifying circulatory indicators will positively improve the prognosis and quality of life of patients with early cancer. Previous studies have shown that miRNA is highly involved in cancer. In addition, miRNA derived from cancers can be encapsulated as exosomes and further extracted into circulatory systems to realize malignant functions. It indicates that circulating exosome-derived miRNAs have the potential to replace conventional biomarkers as cancer derived exosomes carrying miRNAs can be identified by specific markers and might be more stable and accurate for early diagnosis.
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Texto completo:
1
Coleções:
06-national
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ES
Base de dados:
IBECS
Assunto principal:
MicroRNAs
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Diagnóstico Precoce
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Exossomos
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Neoplasias
Idioma:
En
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2022
Tipo de documento:
Article