Relationship of cord blood IgE with maternal, fetal, and environmental factors in the Chinese population
Allergol. immunopatol
; 49(3): 50-55, mayo 2021. tab
Article
em En
| IBECS
| ID: ibc-214264
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Introduction and objectives: Previous studies reported that history of pregnancy and delivery and family environment might influence cord blood IgE (CB-IgE) levels and development of allergies; however, the association between them is not well-established. This study aimed at investigating the IgE level in the newborns umbilical cord blood and its relationship with maternal, fetal, and environmental factors. Materials and methods: A total of 989 mothers and their infants were analyzed in this study. Mothers were given a questionnaire that had a series of questions to evaluate demographic information, maternal allergic status, and environmental exposures during pregnancy. Neonatal cord blood samples were taken at the same time for IgE assay. Results: By univariate analysis, we found statistically significant correlations between CB-IgE levels and gender (P = 0.000) and delivery mode (P = 0.017). By multivariate analysis, gender was found to have a significant association with CB-IgE levels (P = 0.001). No significant difference was found between CB-IgE levels and antenatal complications, the season of birth, birth weight, gestational age, and household income (P > 0.050).Conclusions: In this study, newborn gender was found to be a strong predictor of elevated CB-IgE. The delivery mode was a probable predictor (AU)
Palavras-chave
Texto completo:
1
Coleções:
06-national
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ES
Base de dados:
IBECS
Assunto principal:
Imunoglobulina E
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Sangue Fetal
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Hipersensibilidade
Limite:
Adult
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Female
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Humans
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Male
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Newborn
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Pregnancy
País/Região como assunto:
Asia
Idioma:
En
Revista:
Allergol. immunopatol
Ano de publicação:
2021
Tipo de documento:
Article