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Evaluating the efficacy of Quantum Molecular Resonance (QMR) electrotherapy in mixed-type dry eye patients / Evaluación de la eficacia de la electroterapia de resonancia molecular cuántica (QMR) en pacientes con ojo seco de tipo mixto
Trivli, Alexandra; Karmiris, Efthymios; Dalianis, Georgios; Ruggeri, Alfredo; Terzidou, Chryssa.
Afiliação
  • Trivli, Alexandra; Konstantopouleio-Patission General Hospital. Department of Ophthalmology. Athens. Greece
  • Karmiris, Efthymios; Hellenic Air Force General Hospital. Department of Ophthalmology. Athens. Greece
  • Dalianis, Georgios; Konstantopouleio-Patission General Hospital. Department of Ophthalmology. Athens. Greece
  • Ruggeri, Alfredo; Resono Ophthalmic. Sandrigo. Italy
  • Terzidou, Chryssa; Konstantopouleio-Patission General Hospital. Department of Ophthalmology. Athens. Greece
J. optom. (Internet) ; 16(2): 128-134, Abr-Jun 2023. tab, graf
Artigo em Inglês | IBECS | ID: ibc-218464
Biblioteca responsável: ES1.1
Localização: ES15.1 - BNCS
ABSTRACT

Purpose:

To evaluate the efficacy and safety of the low-power, high-frequency electrical current treatment administered by the Rexon-Eye device, in a cohort of patients affected by mixed-type dry eye disease (DED) of medium to severe level. Patients and

methods:

In this prospective, non-randomized, interventional clinical study, eighteen mixed type DED patients were treated. Treatment was a specific type of electrotherapy, Quantum Molecular Resonance (QMR®), administered by means of the Rexon-Eye® device (Resono Ophthalmic, Sandrigo, Italy) with a protocol of one 20-min session per week, for 4 weeks. Patients were examined at baseline and one month after the last treatment, utilizing the Ocular Surface Disease Index (OSDI) questionnaire and clinical signs non-invasive tear break-up time (NIBUT), Oxford staining, meibum quality, meibography, meibomian gland expressibility, tear meniscus height (TMH), Schirmer's test, ocular inflammation expressed by MMP-9 concentration.

Results:

Subjective benefit in OSDI was reported (p = 0.013). Improvement was also observed in NIBUT (p < 0.001), Oxford staining (p = 0.002), expressible meibomian glands number (p = 0.001) and meibum quality (p < 0.001). A remarkable benefit was present in inflammation, as evidenced by the reduction of MMP-9 (p = 0.003). Changes, although not statistically significant, were also present in TMH (p = 0.076) and Schirmer's test (p = 0.675), whereas no change was observed in meibography score. No adverse event was reported.

Conclusion:

In this mixed-type DED patients’ cohort, Rexon-Eye proved to be effective and safe in improving subjective and objective ocular parameters, as well as capable to normalize inflammatory markers.(AU)
Assuntos


Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Xeroftalmia / Terapia por Estimulação Elétrica / Oftalmopatias / Plug Lacrimal Limite: Humanos Idioma: Inglês Revista: J. optom. (Internet) Ano de publicação: 2023 Tipo de documento: Artigo Instituição/País de afiliação: Hellenic Air Force General Hospital/Greece / Konstantopouleio-Patission General Hospital/Greece / Resono Ophthalmic/Italy

Texto completo: Disponível Coleções: Bases de dados nacionais / Espanha Base de dados: IBECS Assunto principal: Xeroftalmia / Terapia por Estimulação Elétrica / Oftalmopatias / Plug Lacrimal Limite: Humanos Idioma: Inglês Revista: J. optom. (Internet) Ano de publicação: 2023 Tipo de documento: Artigo Instituição/País de afiliação: Hellenic Air Force General Hospital/Greece / Konstantopouleio-Patission General Hospital/Greece / Resono Ophthalmic/Italy
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