Characterization of a group of children with eosinophilic esophagitis in Cali, Colombia
Allergol. immunopatol
; 51(3): 36-41, 01 mayo 2023. tab
Article
em En
| IBECS
| ID: ibc-219811
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Purpose:
Eosinophilic esophagitis (EoE) is an immunologically mediated chronic disease of the gastrointestinal tract. The objective of this study was to clinically and demographically describe a child population with EoE diagnosed in a high-complexity hospital in Cali, Colombia.Methods:
A retrospective study was carried out. The clinical histories of patients between 0 and 18 years with clinical suspicion and a histological diagnosis of EoE were analyzed. All patients underwent an allergy study, either by measurement of specific immunoglobulin (Ig) E and/or an intraepidermal skin-prick test.Results:
Thirty-five patients were included in the study, of which 21 (60%) women. The median age was 8 years (interquartile range [IQR] 512), and the age of onset of symptoms was 5 years (IQR 210). Thirty patients (85.7%) reported a history of allergic disease, with rhinitis being the most frequent (n = 25, 71.4%). Only one patient reported with food allergy mediated by IgE. The main symptoms in patients included abdominal pain (17 [48.6%]), refractory gastroesophageal reflux (16 [45.7%]), and choking (9 [25.7%]). Upper gastrointestinal endoscopy was normal in 10 patients (38.5%). The median number of eosinophils in the biopsy was 42 (IQR 3192). Allergenic sensitization was verified in 25 of 35 patients (71.4%). Of these, dust mite allergy was positive in 21 patients (84%), while the most frequent food allergy was toward cows milk, in five patients (31.3%).Conclusions:
The majority of patients with EoE were females. The most frequent symptom was abdominal pain. Endoscopic abnormalities were also observed frequently, and the prevalence of other allergic diseases (especially rhinitis) and allergenic sensitization (especially to mites) was high (AU)Palavras-chave
Texto completo:
1
Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Esofagite Eosinofílica
/
Hospitalização
Limite:
Child
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Child, preschool
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Female
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Humans
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Male
País/Região como assunto:
America do sul
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Colombia
Idioma:
En
Revista:
Allergol. immunopatol
Ano de publicação:
2023
Tipo de documento:
Article