Exploring il-6 as a marker of respiratory health in athletes: insights from psittacosis pneumonia research
Rev. int. med. cienc. act. fis. deporte
; 23(92): 313-322, aug.-sept. 2023. graf
Artigo
em Inglês
| IBECS
| ID: ibc-229406
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Objective:
This study aims to explore the correlation between interleukin-6 (IL-6) levels and the condition of patients with psittacosis pneumonia, and extend these insights to the context of respiratory health in athletes.Methods:
In a retrospective analysis, we included 14 patients diagnosed with psittacosis pneumonia (parrot fever) treated in our hospital from April 2018 to September 2021 as the study group (SG). As a control group (CG), we selected 20 patients with common pneumonia treated during the same period. We compared IL-6 levels between these groups and recorded changes in IL-6 levels in the SG before and after treatment. Additionally, we analyzed the correlation of IL-6 levels with procalcitonin (PCT) and C-reactive protein (CRP) levels.Results:
The IL-2 levels in the SG were significantly lower than those in the CG, while IL-6 levels were significantly higher. No significant difference was observed in IL-10 and IL-6 levels between the groups (P>0.05). The average IL-6 level in the SG was 80.78±46.20 ng/L before treatment and 7.86±6.73 ng/L after treatment, showing a significant reduction (P<0.05). There was a significant positive correlation between IL-6 levels and PCT levels in the SG (r=0.2659, P<0.05), but the correlation with CRP levels was not significant (r=0.0033, P=0.8465). The Area Under Curve (AUC) of IL-6 for diagnosing psittacosis pneumonia was 0.7929 (P=0.0041).Conclusion:
Patients with psittacosis pneumonia exhibit distinct interleukin level changes, particularly in IL-2 and IL-6, compared to those with ordinary pneumonia. The correlation of IL-6 with PCT levels suggests its potential as a marker in assessing respiratory health conditions, which could be relevant for monitoring respiratory health in athletes, given the heightened susceptibility to respiratory issues in this group (AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Psitacose
/
Pneumonia Bacteriana
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. int. med. cienc. act. fis. deporte
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
Wenzhou Medical University/China