The modulation effects of the mind-body and physical exercises on the basolateral amygdala-temporal pole pathway on individuals with knee osteoarthritis / Los efectos de modulación de la mente-cuerpo y los ejercicios físicos en la vía del polo basolateral amígdala-temporal en personas con osteoartritis de rodilla
Int. j. clin. health psychol. (Internet)
; 24(1): [100421], Ene-Mar, 2024. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-230363
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Background/Objective:
To investigate the modulatory effects of different physical exercise modalities on connectivity of amygdala subregions and its association with pain symptoms in patients with knee osteoarthritis (KOA).Methods:
140 patients with KOA were randomly allocated either to the Tai Chi, Baduanjin, Stationary cycling, or health education group and conducted a 12 week-long intervention in one of the four groups. The behavioral, magnetic resonance imaging (MRI), and blood data were collected at baseline and the end of the study.Results:
Compared to the control group, all physical exercise modalities lead to significant increases in Knee Injury and Osteoarthritis Outcome Score (KOOS) pain score (pain relief) and serum Programmed Death-1 (PD-1) levels. Additionally, all physical exercise modalities resulted in decreased resting state functional connectivity (rsFC) of the basolateral amygdala (BA)-temporal pole and BA-medial prefrontal cortex (mPFC). The overlapping BA-temporal pole rsFC observed in both Tai Chi and Baduanjin groups was significantly associated with pain relief, while the BA-mPFC rsFC was significantly associated with PD-1 levels. In addition, we found increased fractional anisotropy (FA) values, a measurement of water diffusion anisotropy of tissue that responded to changes in brain microstructure, within the mind-body exercise groups' BA-temporal pole pathway. The average FA value of this pathway was positively correlated with KOOS pain score at baseline across all subjects.Conclusions:
Our findings suggest that physical exercise has the potential to modulate both functional and anatomical connectivity of the amygdala subregions, indicating a possible shared pathway for various physical exercise modalities.(AU)
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Dor
/
Medição da Dor
/
Exercício Físico
/
Osteoartrite do Joelho
/
Terapia por Exercício
/
Complexo Nuclear Basolateral da Amígdala
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Int. j. clin. health psychol. (Internet)
Ano de publicação:
2024
Tipo de documento:
Artigo
Instituição/País de afiliação:
Fujian University of Traditional Chinese Medicine/China