Antibiomania: A Case Report of a Manic Episode Potentially Induced by the Interaction of Clarithromycin and Amoxicillin during H. Pylori Eradication Therapy
Actas esp. psiquiatr
; 52(1): 57-59, Feb. 2024.
Article
em En
| IBECS
| ID: ibc-231257
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Antibiomanic episodes, or as the DSM-5 refers to them, drug-induced manic episodes, pose a clinical challenge that is still poorly understood. There is insufficient information on the most common clinical presentation, patient profile, or underlying aetiopathogenic mechanisms. We present the clinical case of a 67-year-old woman who, after starting treatment (clarithromycin and amoxicillin) for the eradication of Helicobacter pylori, bacteria presented with a brief manic episode, which resolved after withdrawal of both drugs and with antipsychotic treatment. The possible interaction of both drugs, as GABA antagonists, in the generation of such episodes is discussed, and the clinical importance of such episodes in psychiatric emergency departments and liaison and interconsultation psychiatry, is highlighted. (AU)
Palavras-chave
Texto completo:
1
Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Transtorno Bipolar
/
Claritromicina
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Interações Medicamentosas
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Amoxicilina
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Actas esp. psiquiatr
Ano de publicação:
2024
Tipo de documento:
Article