Creatine feeding does not enhance intramyocellular glycogen concentration during carbohydrate loading: an in vivo study by 31P- and 13C-MRS
J. physiol. biochem
; 64(3): 189-196, jul.-sept. 2008. tab
Artigo
em Inglês
| IBECS
| ID: ibc-61823
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
The main aim of this study was to examine the hypothesis that creatine (Cr) feedingenhances myocellular glycogen storage in humans undergoing carbohydrateloading. Twenty trained male subjects were randomly assigned to have their dietssupplemented daily with 252 g of glucose polymer (GP) and either 21 g of Cr (CRGP,n=10) or placebo (PL-GP, n=10) for 5 days. Changes in resting myocellularglycogen and phosphocreatine (PCr) were determined with Magnetic ResonanceSpectroscopy (13C- and 31P-MRS, respectively). After CR-GP, the levels of intramyocellularglycogen increased from 147 ± 13 (standard error) mmol·(kg wet weight-1)to 172 ± 13 mmol·(kg wet weight)-1, while it increased from 134 ± 17 mmol·(kg wetweight)- to 182 ± 17 mmol·(kg wet weight)-1 after PL-GP; the increments in intramyocellularglycogen concentrations were not statistically different. The increment inthe PCr/ATP ratio after CR-GP (+ 0.20 ± 0.12) was significantly different comparedto PL-GP (- 0.34 ± 0.16) (p<0.05). The present results do not support the hypothesisthat Cr loading increases muscle glycogen storage (AU)
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Espanha
Base de dados:
IBECS
Assunto principal:
Ingestão de Energia
/
Adenosina
/
Fibras Musculares Esqueléticas
/
Creatina
/
Metabolismo dos Carboidratos
/
Glucanos
/
Glicogênio
Tipo de estudo:
Ensaio clínico controlado
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
J. physiol. biochem
Ano de publicação:
2008
Tipo de documento:
Artigo
Instituição/País de afiliação:
Paul Scherrer Institute/Switzerland
/
University Autonoma of Barcelona/Spain
/
University of Zurich/Switzerland