Mionecrosis de la extremidad inferior por Clostridium septicum en paciente con leucemia mieloide aguda / Lower limb myonecrosis due to Clostridium septicum in a patient with acute myeloid leukemia

ABSTRACT

Purpose and clinical case. This is a clinical case of a 64 year-old patient diagnosed with acute myeloid leukemia (AML) with medullary aplasia who developed infectious soft tissue necrosis (ISTN) of the right thigh in a time-frame of 12 hours. An emergency fasciotomy and radical debridement of the affected limb were carried out and antibiotic treatment with penicillin was initiated. Four hours after surgery the patient died. Conclusions. The unique nature of this case lies in the fact that on autopsy lower limb myonecrosis was found, caused by contiguity to necrotizing enterocolitis caused by Clostridium septicum in an immunodepressed patient, a fact that undoubtedly contributed to the rapid clinical progress of the condition and its end-result, in spite of the treatment applied (AU)