Nuevos fármacos antirretrovirales: inhibidores del CCR5 y de la integrasa / New CCR5 inhibitor antiretroviral drugs and integrase inhibitors

ABSTRACT

Two new antiretroviral drugs belonging to a newdrug family have recently been marketed in Spain.These are maraviroc (CCR5 correceptor inhibitor)and raltegravir (integrase inhibitor). These have theadvantage of not presenting crossed resistance withother previously administered antiretroviral drugs,converting them into the cornerstone of the rescuetreatment in the patient infected by a multiresistantviral strain. The scientific evidence available onthese two drugs is reviewed in this work and its indications in the HIV infected patient are discussed (AU)