Epidemiology and treatment of adenoid cystic carcinoma of the minorsalivary glands: A meta-analytic study

ABSTRACT

Objectives: To evaluate the epidemiological aspects of adenoid cystic carcinoma (ACC) and to evaluate the differenttherapeutic possibilities as well as the percentage of survival.Study Design: A retrospective, meta-analytic, observational study was carried out by selecting a total of 13 articles,which provided a sample size of 263 cases of patients who had been diagnosed with ACC in the minorsalivary glands.Results: ACC was found to be more common among women (56.5%) and the average age at diagnosis was 55.26years old. The primary location of the tumor was in the palate in 57% of the cases, the predominant pattern beingcribiform. The treatment of choice was therapy combined with surgery and radiotherapy in 62.7% of the subjects.The overall survival rate was 70.76% and 56.76%, at 5 and 10 years respectively.Conclusions: Early detection of adenoid cystic carcinoma is necessary in order to enable making an earlier prognosis and thus enable a better quality of life for the patient (AU)