Comparison of inflammation markers and severity of illness among patients with COVID-19, acute psychiatric disorders and comorbidity
Eur. j. psychiatry
; 37(2): 125-132, abril-junio 2023. tab
Article
em En
| IBECS
| ID: ibc-219647
Biblioteca responsável:
ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Background and objectives: Neutrophil, lymphocyte counts, lactate dehydrogenase (LDH), D-dimer, fibrinogen, and comorbid illness are associated with the course and prognosis of COVID-19. However, the course of acute severe psychiatric disorders overlapping with COVID-19 infection was not investigated and remained as an unclarified research area. This study aimed to demonstrate inflammatory markers and the course of patients suffering from both conditions.MethodsThirty-eight inpatients with COVID-19 and comorbid acute psychiatric disorders (COVID-19+PD), 31 inpatients with COVID-19, and 38 inpatients with an acute psychiatric disorder (PD) were included in the study. Neutrophil, lymphocyte counts, serum ferritin, lactate dehydrogenase (LDH), D-dimer, fibrinogen, Systemic immune-inflammation index (SII), neutrophil/lymphocyte ratio (NLR), and C-reactive protein (CRP) were compared to evaluate inflammation levels.ResultsPatients with SARS-CoV-2 infection had older age compared to the PD group. CALL (Comorbidity, age, lymphocyte, lactate dehydrogenase) scores which predict the progression risk in patients with COVID-19 pneumonia, of both COVID-19 groups were found similar. The COVID-19+PD had higher SII in the study sample. Additionally, the COVID-19+PD group had higher NLR, ferritin, and CRP levels than those of the PD group.ConclusionsThe prognosis of COVID-19 is not worse when accompanied by a psychiatric disorder. Laboratory assessment can guide clinicians to distinguish those infected with SARS-CoV-2 within psychiatric inpatient units. The biochemical assessment did not robustly support higher inflammatory levels in the comorbid COVID-19 and psychiatric disorder group compared to the COVID-19 group. (AU)
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Texto completo:
1
Coleções:
06-national
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ES
Base de dados:
IBECS
Assunto principal:
Infecções por Coronavirus
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Coronavírus Relacionado à Síndrome Respiratória Aguda Grave
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Pacientes
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Exame Físico
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Psicotrópicos
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Ensino
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Transfusão de Sangue Autóloga
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Comorbidade
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Coronavirus
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Hepatite Autoimune
Limite:
Humans
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Female
Idioma:
En
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Es
Revista:
An. R. Acad. Nac. Farm. (Internet)
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Eur. j. psychiatry
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Med. clín (Ed. impr.)
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Rev. esp. enferm. dig
Ano de publicação:
2022
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2023
Tipo de documento:
Article