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Comparison of inflammation markers and severity of illness among patients with COVID-19, acute psychiatric disorders and comorbidity
Tuna, Özgecan; Ermis, Cagatay; Enez Darcin, Asli; Dagistan, Ekin; Salman, Serdar.
Afiliação
  • Tuna, Özgecan; Kanuni Sultan Süleyman Training and Research Hospital. Turkey
  • Ermis, Cagatay; Diyarbakır Childrens' Hospital. Turkey
  • Enez Darcin, Asli; İstanbul Ayvansaray University. İstanbul. Turkey
  • Dagistan, Ekin; Istanbul Bakirkoy Prof Dr. Mazhar Osman Ruh Mental and Nervous Diseases Training and Research Hospital. Istanbul. Turkey
  • Salman, Serdar; Istanbul Bakirkoy Prof Dr. Mazhar Osman Ruh Mental and Nervous Diseases Training and Research Hospital. Istanbul. Turkey
Eur. j. psychiatry ; 37(2): 125-132, abril-junio 2023. tab
Article em En | IBECS | ID: ibc-219647
Biblioteca responsável: ES1.1
Localização: ES15.1 - BNCS
ABSTRACT
Background and objectives: Neutrophil, lymphocyte counts, lactate dehydrogenase (LDH), D-dimer, fibrinogen, and comorbid illness are associated with the course and prognosis of COVID-19. However, the course of acute severe psychiatric disorders overlapping with COVID-19 infection was not investigated and remained as an unclarified research area. This study aimed to demonstrate inflammatory markers and the course of patients suffering from both conditions.MethodsThirty-eight inpatients with COVID-19 and comorbid acute psychiatric disorders (COVID-19+PD), 31 inpatients with COVID-19, and 38 inpatients with an acute psychiatric disorder (PD) were included in the study. Neutrophil, lymphocyte counts, serum ferritin, lactate dehydrogenase (LDH), D-dimer, fibrinogen, Systemic immune-inflammation index (SII), neutrophil/lymphocyte ratio (NLR), and C-reactive protein (CRP) were compared to evaluate inflammation levels.ResultsPatients with SARS-CoV-2 infection had older age compared to the PD group. CALL (Comorbidity, age, lymphocyte, lactate dehydrogenase) scores which predict the progression risk in patients with COVID-19 pneumonia, of both COVID-19 groups were found similar. The COVID-19+PD had higher SII in the study sample. Additionally, the COVID-19+PD group had higher NLR, ferritin, and CRP levels than those of the PD group.ConclusionsThe prognosis of COVID-19 is not worse when accompanied by a psychiatric disorder. Laboratory assessment can guide clinicians to distinguish those infected with SARS-CoV-2 within psychiatric inpatient units. The biochemical assessment did not robustly support higher inflammatory levels in the comorbid COVID-19 and psychiatric disorder group compared to the COVID-19 group. (AU)
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Texto completo: 1 Coleções: 06-national / ES Base de dados: IBECS Assunto principal: Infecções por Coronavirus / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Pacientes / Exame Físico / Psicotrópicos / Ensino / Transfusão de Sangue Autóloga / Comorbidade / Coronavirus / Hepatite Autoimune Limite: Humans / Female Idioma: En / Es Revista: An. R. Acad. Nac. Farm. (Internet) / Eur. j. psychiatry / Med. clín (Ed. impr.) / Rev. esp. enferm. dig Ano de publicação: 2022 / 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 06-national / ES Base de dados: IBECS Assunto principal: Infecções por Coronavirus / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Pacientes / Exame Físico / Psicotrópicos / Ensino / Transfusão de Sangue Autóloga / Comorbidade / Coronavirus / Hepatite Autoimune Limite: Humans / Female Idioma: En / Es Revista: An. R. Acad. Nac. Farm. (Internet) / Eur. j. psychiatry / Med. clín (Ed. impr.) / Rev. esp. enferm. dig Ano de publicação: 2022 / 2023 Tipo de documento: Article