Modificación del perfil lipídico de la placenta humana por efecto de la desnutrición materna moderada / Modification of lipidic profile of human placenta by effects of moderate maternal undernutrition
Rev. méd. Chile
; 122(5): 503-9, mayo 1994. tab
Artigo
em Espanhol
| LILACS
| ID: lil-135456
Biblioteca responsável:
CL1.1
ABSTRACT
The lipid composition of human placenta phospholipids, coming from 9 undernourished women that gave birth to low weight newborns and 9 well norished women, was analyzed using gas-liquid chromatography. Phospholipids of placentas coming from undernourished women, when compared to well nourished women, had significantly lower amounts of w-6 and w-3 fatty acids (40.1 ñ 1.5 vs 42.4 ñ 1.4 and 6.0 ñ 0.7 vs 7.1 ñ 1,3 per cent respectively). The calculated mean melting point was higher in placentas coming from undernourished women. In these women, the low content of polyunsaturated fatty acids and its replacement by short chain fatty acids was not able to balance the high mean melting points. The relative deficiency of essencial fatty acids, the low saturation index and the high mean melting point of undernourished women's placental phospholipids, may suggest a lower membrane fluidity and a subnormal essencial fatty acid content of fetal organs, that are essencial for normal growth and development
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Fosfolipídeos
/
Placenta
/
Doenças Placentárias
/
Lipídeos
/
Distúrbios Nutricionais
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Recém-Nascido
/
Gravidez
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
1994
Tipo de documento:
Artigo