The stabilizing effects of the acquired immunity on the schistosomiasis transmission modeling - the sensitivity analysis
Mem. Inst. Oswaldo Cruz
; 93(supl.1): 63-73, Oct. 1998. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-218644
Biblioteca responsável:
BR15.1
RESUMO
A mathematical model is proposed to analyze the effects of acquired immunity on the transmission of schistosomiasis in the human host. From this model the prevalence curve dependent on four parameters can be obtained. These parameters were estimuted fitting the data by the maximum likehood method. The model showed a good retrieving capacity of real data from two endemic areas of schistosomiasis Touros, Brazil (Schistosoma mansoni) and Misungwi, Tanzania (S. haematobium). Also, the average worm burden per person and the dispersion of parasite per person in the community can be obtained from the model. In this paper, the stabilizing effects of the acquired immunity assumption in the model are assessed in terms of the epidemiological variables as follows. Regarded to the prevalence curve, we calculate the confidence interval, and related to the average worm burden and the worm dispersion in the community, the sensitivity analysis (the range of the variation) of both variables with respect to their parameters is performed.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Helmintíase
/
Doenças Negligenciadas
/
Esquistossomose
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Esquistossomose
/
Tanzânia
/
Brasil
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
África
/
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
1998
Tipo de documento:
Artigo
/
Congresso e conferência