Prevalence of Trypanosoma cruzi and Leishmania chagasi infection and risk factors in a Colombian indigenous population
Rev. Inst. Med. Trop. Säo Paulo
; 41(4): 229-34, July-Aug. 1999.
Artigo
em Inglês
| LILACS
| ID: lil-246831
Biblioteca responsável:
BR1.1
RESUMO
This study was carried out in order to obtain base-line data concerning the epidemiology of American Visceral Leishmaniasis and Chagas's Disease in an indigenous population with whom the government is starting a dwelling improvement programme. Information was collected from 242 dwellings (1,440 people), by means of house to house interviews about socio-economic and environmental factors associated with Leishmania chagasi and Trypanosoma cruzi transmission risk. A leishmanin skin test was applied to 385 people and 454 blood samples were collected on filter paper in order to detect L. chagasi antibodies by ELISA and IFAT and T. cruzi antibodies by ELISA. T. cruzi seroprevalence was 8.7 percent by ELISA, L. chagasi was 4.6 percent and 5.1 pecent by IFAT and ELISA, respectively. ELISA sensitivity and specificity for L. chagasi antibodies were 57 percent and 97.5 percent respectively, as compared to the IFAT. Leishmanin skin test positivity was 19 percent. L. chagasi infection prevalence, being defined as a positive result in the three-immunodiagnostic tests, was 17.1 percent. Additionally, 2.7 percent of the population studied was positive to both L. chagasi and T. cruzi, showing a possible cross-reaction. L. chagasi and T. cruzi seropositivity increased with age, while no association with gender was observed. Age (p<0.007), number of inhabitants (p<0.05), floor material (p<0.03) and recognition of vector (p<0.01) were associated with T. cruzi infection, whilst age ( p<0.007) and dwelling improvement (p<0.02) were associated with L. chagasi infection. It is necessary to evaluate the long-term impact of the dwelling improvement programme on these parasitic infections in this community
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doença de Chagas
/
Doenças Negligenciadas
Base de dados:
LILACS
Assunto principal:
Trypanosoma cruzi
/
Doença de Chagas
/
Leishmania
/
Leishmaniose Visceral
Tipo de estudo:
Estudo diagnóstico
/
Estudo de etiologia
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Limite:
Animais
/
Humanos
País/Região como assunto:
América do Sul
/
Colômbia
Idioma:
Inglês
Revista:
Rev. Inst. Med. Trop. Säo Paulo
Assunto da revista:
Medicina Tropical
Ano de publicação:
1999
Tipo de documento:
Artigo