Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncósferas de taenia solium / Study on immune humoral response in pigs infected with eggs and posoncospheres of taenia solium
Bol. chil. parasitol
; 54(3/4): 57-62, jul.-dic. 1999. tab, graf
Artigo
em Espanhol
| LILACS
| ID: lil-267624
Biblioteca responsável:
CL1.1
RESUMO
Due to the importance of cysticercosis in Mexico and Latin America and to the fact that in the last years another mechanism of infection for this disease has been proposed, i.e. through postoncospheres and immunosuppression of the host, we have considered relevant to perform the present work, which consisted in assessing the immune response induced by dexamethasone as well as that produced by parasites in pigs infected with T. solium eggs, or postoncosphere-infected, and in postoncosphere-infected and dexamethasone treated animals. We used 10 recently weaned pigs, three were used as controls, two of them without the drug and one with it; two were infected with T. solium eggs; five with postoncospheres receiving also dexamethasone three of them. We evaluated the humoral response against parasite antigen using indirect haemagglutination (IH) and ELISA methods. Results of the immune humoral response revealed titres of up to 1128 in T. solium eggs infected animals, of 116 in postoncosphere infected animals. Absorbance titres with of 132 towards the end of the experiment in postoncosphere plus dexamethasone animals. Absorbance titres with Elisa confirmed these findings. Data obtained by IH show that the antibody titres of the pigs challenged with postoncospheres and postoncospheres plus dexamethasone are positive as compared to the titres obtained in the pigs infected with T. solium eggs. Results from the Elisa confirmed this finding, since, from weeks 14 to 17, the pigs became positive, behaving as those pigs that developed cysticercosis. This is revelant as it indicates that the antiposcosphere antibodies recognized antigens of T. solium larvae
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
Doenças Negligenciadas
Problema de saúde:
Meta 3.3: Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
Doenças Negligenciadas
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Taenia
/
Cisticercose
/
Formação de Anticorpos
Limite:
Animais
Idioma:
Espanhol
Revista:
Bol. chil. parasitol
Assunto da revista:
ALIMENTOS
/
Parasitologia
Ano de publicação:
1999
Tipo de documento:
Artigo
País de afiliação:
México