Potential incorporation of 5-aminolevulinic acid in micelles and stratum corneum lipids liposomes: fluorescence quenching studies
RBCF, Rev. bras. ciênc. farm. (Impr.)
; 37(3): 356-361, set.-dez. 2001. graf
Artigo
em Inglês
| LILACS
| ID: lil-314058
Biblioteca responsável:
BR40.1
ABSTRACT
The quenchings of pyrene fluorescence by 5-aminolevulinic acid (5-ALA) in dodecyl sulfate (SDS) micelles and stratum corneum lipids liposomes (SCLLs) were studied in order to verify the capacity of incorporation of 5-ALA in these systems. Static and dynamic quenching constants based on the simultaneous determination of fluorescence intensity quenching and fluorescence decay measurements were determined. 5-ALA was incorporated at crescent concentrations in SDS micelles and SCLLs containing the fluorescent probe (pyrene, 1,15 x '10 POT.menos 5 M') and the rate constants of quenching (kq) of pyrene were determined. 5-ALA was able to quench the fluorescence of the probe in both systems studied. A greater extent...
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Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Fotoquimioterapia
/
Pirenos
/
Neoplasias Cutâneas
/
Fluorescência
/
Ácido Aminolevulínico
Idioma:
Inglês
Revista:
RBCF, Rev. bras. ciênc. farm. (Impr.)
Assunto da revista:
Bioquímica
/
Farmácia
/
Farmacologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade de São Paulo/BR