Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana / Correlation between CA-125 marker and the presence and severity of pelvic endometriosis
Rev. méd. Chile
; 131(4): 367-372, abr. 2003. tab, graf
Artigo
em Espanhol
| LILACS
| ID: lil-348363
Biblioteca responsável:
CL1.1
ABSTRACT
Background:
Endometriosis affects at least 15 percent of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis.Aim:
To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy. Patients andmethods:
A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease.Results:
Sixty nine patients had endometriosis (59 percent ). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease.Discussion:
The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Biomarcadores Tumorais
/
Endometriose
Tipo de estudo:
Estudo observacional
/
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Espanhol
Revista:
Rev. méd. Chile
Assunto da revista:
Medicina
Ano de publicação:
2003
Tipo de documento:
Artigo
País de afiliação:
Chile
Instituição/País de afiliação:
Pontificia Universidad Católica de Chile/CL