1, 5-anhydroglucitol levels in type 2 diabetic and non-diabetic subjects in southern Taiwan
Arq. bras. endocrinol. metab
; 47(6): 711-715, dez. 2003. tab
Article
em En
| LILACS
| ID: lil-356035
Biblioteca responsável:
BR1.2
RESUMO
PURPOSES:
To estimate plasma 1,5-anhydroglucitol (AG) in diabetic (DM) and non-DM patients in a Chinese population, and to compare it with fructosamine, glycosylated hemoglobin (HbA1c), and fasting glucose (FG) levels.METHODS:
Case-control study on the significance of AG conducted in a medical center of southern Taiwan, including356 patients (300 non-DM and 56 type 2 DM). Plasma AG, fructosamine, HbA1c and FG were measured on the second day of admission and only those with normal values (except glucose) were enrolled. Glycemic markers of the non-DM patients were examined only once whereas DM patients were sequentially sampled over 3 months.RESULTS:
Mean plasma AG levels were lower in DM than in non-DM patients (4.02+/-2.96 vs 26.68+/-11.33µg/ml, P<0.001), and lower in non-DM females than males (22.90+/-9.51 vs 29.45+/-11.7µg/ml, P<0.05). AG showed a good correlation with FG. Mean plasma AG were inversely correlated with FG, fructosamine and HbA1c in DM patients and worked as well as other glycemic markers in detecting short-term changes in glycemic control. AG levels of DM patients demonstrated no difference with or without smoking, hypertension, micro- and macro-vascular complications.CONCLUSIONS:
We recommend clinical application of plasma AG in long-standing DM patients for short-term detection and monitoring glycemic condition.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Desoxiglucose
/
Diabetes Mellitus Tipo 2
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arq. bras. endocrinol. metab
Assunto da revista:
ENDOCRINOLOGIA
/
METABOLISMO
Ano de publicação:
2003
Tipo de documento:
Article
/
Project document
País de afiliação:
China
País de publicação:
Brasil