Complete response of metastatic renal cancer with dendritic cell vaccine
Int. braz. j. urol
; 29(6): 517-519, Nov.-Dec. 2003. ilus
Artigo
em Inglês
| LILACS
| ID: lil-364406
Biblioteca responsável:
BR1.1
ABSTRACT
INTRODUCTION:
We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate.DISCUSSION:
The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Int. braz. j. urol
Assunto da revista:
Urologia
Ano de publicação:
2003
Tipo de documento:
Artigo
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Documento de projeto