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Complete response of metastatic renal cancer with dendritic cell vaccine
Dall'Oglio, Marcos; Srougi, Miguel; Barbuto, José A. M.
Afiliação
  • Dall'Oglio, Marcos; s.af
  • Srougi, Miguel; s.af
  • Barbuto, José A. M; s.af
Int. braz. j. urol ; 29(6): 517-519, Nov.-Dec. 2003. ilus
Artigo em Inglês | LILACS-Express | LILACS | ID: lil-364406
Biblioteca responsável: BR1.1
ABSTRACT

INTRODUCTION:

We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma, evolved with recurrence of the neoplasia in January 2002, confirmed by resection of the lesion. A vaccine therapy based on dendritic cells was then performed during 5 months (4 applications). After this period, there was occurrence of new lesions, whose resection revealed areas of necrosis and inflammatory infiltrate.

DISCUSSION:

The outcome of renal cell carcinoma is influenced by prognostic factors that confer more aggressive tumor characteristics. However, in cases of recurrence, the systemic therapy with dendritic cells-based vaccine can be associated with a better outcome with regression of disease.
Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2003 Tipo de documento: Artigo / Documento de projeto

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Inglês Revista: Int. braz. j. urol Assunto da revista: Urologia Ano de publicação: 2003 Tipo de documento: Artigo / Documento de projeto
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