Sandimmun vs Neoral: comparación entre dos tipos de Ciclosporina en pacientes con trasplante de riñón / Sandimmun vs Neoral: comparison between two types of cyclosporine in patients with kidney transplantation
Rev. méd. Panamá
; 25: 38-41, 2000.
Article
em Es
| LILACS
| ID: lil-409781
Biblioteca responsável:
BR1.1
ABSTRACT
We present a comparative trial between Sandimmun, the original cyclosporine presentation, and a modified one, called Neoral, in microemulsion, to increase the blood absortion and stability of the product. We built for each product, an absorption kinetic curve and we applied it to three patients with stable renal function, using the same dosage that was used for ciclosporine. We observed a greater absorption and stability in the blood levels of Neoral. We analyzed hundred blood samples in 25 patients and we found a higher level of this product; this lead us to make possible that in 72% of the patients we could diminish the daily dosis in 5 to 10%. The patient's renal function was stable and no complications or secondary effects were present with Neoral.
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Transplante de Rim
/
Ciclosporina
/
Imunossupressores
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev. méd. Panamá
Assunto da revista:
MEDICINA
Ano de publicação:
2000
Tipo de documento:
Article
País de publicação:
Panamá