Association of GH and IGF-1 polymorphisms with growth traits in a synthetic beef cattle breed
Genet. mol. biol
; 28(2): 230-236, 2005. tab, graf
Artigo
em Inglês
| LILACS
| ID: lil-416290
Biblioteca responsável:
BR1.1
ABSTRACT
The Canchim beef cattle (5/8 Charolais + 3/8 Zebu) has been selected for meat production in Brazil since late 1950. In the present work the effects of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) polymorphisms were investigated in 688 animals born between 1998 and 2000. These animals belonged to two genetic groups, i.e., traditional and new lineages. Genotype effects on expected breeding values for birth weight (BW), weaning weight (WW) and yearling weight (YW) were investigated by the least square method. Significant effects were found for GH genotype on YW (p < 0.05), with positive effects associated with the LV (leucine/valine) genotype. For IGF-1 genotypes, significant effects were found on BW (p < 0.01) and YW (p < 0.01). Average substitution effects for IGF-1 alleles estimated by regression analysis suggested a positive effect of the IGF-1 225 bp allele on BW and of the 229 bp allele on YW.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Fator de Crescimento Insulin-Like I
/
Bovinos
/
Hormônio do Crescimento
Tipo de estudo:
Fatores de risco
Limite:
Animais
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Genet. mol. biol
Assunto da revista:
Genética
Ano de publicação:
2005
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
Instituição/País de afiliação:
Embrapa Pecuária Sudeste/BR
/
Universidade Estadual de São Paulo/BR
/
Universidade Federal de São Carlos/BR