Fos-like immunoreactivity in central nervous system of mice simultaneously exposed to the elevated plus-maze and nociception
RBCF, Rev. bras. ciênc. farm. (Impr.)
; 41(3): 385-391, jul.-set.2005. ilus, graf
Article
em En
| LILACS
| ID: lil-427934
Biblioteca responsável:
BR40.1
ABSTRACT
It has been demonstrated that mice exhibit antinociception when they are exposed to the elevated plus-maze (EPM), an animal model of anxiety. To investigate which brain structures are activated during EPM exposure, the present study assessed the immunohistochemical staining for Fos-like immunoreactivity (Fos-LI) in mice intraperitoneally injected with saline or 0,6 por cente acetic acid (which produces nociception) and cofined in the open arm (threatening situation) or enclosed arm (Control) of the EPM. The following strutuctures were investigated magnus, dorsal and median raphe nuclei (MR, DR and MnR), periaqueductal gray matter (PAG), dorsal and ventral hippocampus (DH and VH), amygdala (AMY), hypothalamus (HYP) and superior and inferior colliculi (SC and IC)...
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Medição da Dor
/
Sistema Nervoso Central
/
Genes fos
/
Aprendizagem em Labirinto
/
Medo
/
Animais de Laboratório
Limite:
Animals
Idioma:
En
Revista:
RBCF, Rev. bras. ciênc. farm. (Impr.)
Assunto da revista:
BIOQUIMICA
/
FARMACIA
/
FARMACOLOGIA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Brasil