Síndrome hemolítico urémico: Experiencia de un centro pediátrico / Hemolytic uremic syndrome: The experience of a pediatric center
Rev. méd. Chile
; 133(7): 781-787, jul. 2005. tab
Article
em Es
| LILACS
| ID: lil-429137
Biblioteca responsável:
BR1.1
ABSTRACT
Background:
Hemolytic uremic syndrome (HUS) is one of the main causes of acute renal failure in the Chilean pediatric population.Aim:
To report the features of patients with HUS, admitted to the pediatric ward of a clinical hospital. Material andmethods:
Retrospective review of medical records of patients admitted with the diagnosis of HUS between 1995 and 2002.Results:
During the period, 58 patients were admitted with the diagnosis of HUS but only 43 (age range 1 month to 6 years, 22 females) had complete medical records for review. Ninety five percent presented with prodromic diarrhea, mainly dysenteric. Antibiotics were administered to 70%, in the previous days. Acute renal replacement, mainly peritoneal dialysis, was required in 40%. The clinical signs and laboratory parameters that correlated better with the indication for dialysis were anuria, hypertension, initial and permanently high serum creatinine and blood urea nitrogen. Four patients with blood urea nitrogen over 100 mg/dl but without anuria or hyperkalemia, were treated conservatively, and experienced an uneventful course (permissive azotemia). Hospital stay was almost 3 times greater in dialyzed than in non dialyzed children. No deaths related to HUS were reported in the study period. In an average follow up of 54 months, 11.6% of the patients developed chronic renal failure of diverse magnitude.Conclusions:
Despite the fact that our study group behaved clinically similar to published HUS patients in other series, no mortality was observed in a retrospective analysis of patients with this disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Injúria Renal Aguda
/
Síndrome Hemolítico-Urêmica
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
Es
Revista:
Rev. méd. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile