Las lesiones placentarias en la infección humana por Trypanosoma cruzi / Placental lesions in human Trypanosoma cruzi infection
Rev. Soc. Bras. Med. Trop
; 38(supl.2): 84-86, 2005. ilus
Article
em Es
| LILACS
| ID: lil-444169
Biblioteca responsável:
BR1.1
ABSTRACT
This histopathological study analyzes placentas of babies congenitally infected with T. cruzi (M+B+), or babies not infected but born from infected- (M+B-), or non infected-mothers (M-B-). Placentas M+B+ showed lesions of chorionitis, chorioamnionitis and cord edema with lymphocyte infiltration, whereas such lesions were infiltrated only with polymorphonuclear cells in M+B- and M-B- placentas. Parasites were found in M+B+ placentas, in fibroblasts and macrophages of chorion, membranes, chorionic plate, mainly in the area of membrane insertion, as well as in cells of Wharton jelly and myocytes of umbilical cord vessels. These results suggest that the materno-fetal transmission of parasites occurs mainly through the marginal sinus, spreading into the chorionic plate infecting fibroblasts and macrophages so far as to found a fetal vessel, inducing a fetal infection by hematogenous route.
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Placenta
/
Trypanosoma cruzi
/
Corioamnionite
/
Doença de Chagas
/
Complicações Parasitárias na Gravidez
/
Transmissão Vertical de Doenças Infecciosas
Limite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
Es
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
MEDICINA TROPICAL
Ano de publicação:
2005
Tipo de documento:
Article
/
Congress and conference
País de afiliação:
Bélgica
/
Bolívia