Retrospective study comparing six - and twelve-core prostate biopsy in detection of prostate cancer
Int. braz. j. urol
; 34(1): 9-14, Jan.-Feb. 2008. tab
Article
em En
| LILACS
| ID: lil-482937
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
We compared the safety and efficacy of the 12-core biopsy with those of the conventional systematic 6-core biopsy with PSA levels between 4.1 and 20.0 ng/mL. MATERIALS ANDMETHODS:
This study included 428 patients who underwent a 6-core biopsy and 128 patients who underwent a 12-core biopsy. Biopsies were performed transrectally under ultrasound guidance. The 12-core biopsy scheme involved obtaining 6 far lateral cores.RESULTS:
For patients with PSA level between 4.1 and 10.1 ng/mL, 47 of the 265 patients who underwent 6-core biopsy and 32 of the 91 patients who underwent a12-core biopsy were diagnosed with prostate cancer (p = 0.0006). Among the patients with a PSA level between 10.1 and 20.0 ng/mL, 48 of 163 patients who underwent the 6-core biopsy and 16 of 37 patients who underwent the 12-core biopsy were diagnosed with prostate cancer (p = 0.0606). Three of the 95 patients who were diagnosed with prostate cancer through the 6-core biopsy and 12 of the 48 patients who were diagnosed through the 12-core biopsy had cancer located in the anterior apex. The 12-core biopsy increased the diagnostic rate in the apex (p = 0.001). No statistically significant differences were found in incidence of complications.CONCLUSION:
We concluded that the 12-core biopsy is a safe and more effective procedure for increasing the diagnostic rate of prostate cancer than the 6-core biopsy in patients with PSA level between 4.1 and 10.0 ng/mL, and the most useful anatomical area to be added was found to be cores from the anterior apex.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Próstata
/
Neoplasias da Próstata
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Biópsia por Agulha
Tipo de estudo:
Diagnostic_studies
/
Guideline
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Observational_studies
/
Risk_factors_studies
Limite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Int Braz J Urol
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Int. braz j urol (Online)
/
Int. braz. j. urol
/
International braz j urol (Impresso)
/
International brazilian journal of urology
Assunto da revista:
UROLOGIA
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Japão
País de publicação:
Brasil