Occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing head and neck radiotherapy
Braz. j. microbiol
; 42(3): 1047-1055, July-Sept. 2011. tab
Artigo
em Inglês
| LILACS
| ID: lil-607534
Biblioteca responsável:
BR32.1
ABSTRACT
The aim of this study was to evaluate the occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing radiotherapy (RT) for treatment of head and neck cancer. Fifty patients receiving RT were examined before, during and 30 days after RT. Saliva, mucosa, and biofilm samples were collected and microorganisms were detected by culture and polymerase chain reaction (PCR). The most prevalent yeasts in patients submitted to RT were Candida albicans, C. tropicalis, C. krusei, C. glabrata and C. parapsilosis. Citrobacter, Enterobacter, Enterococcus, Klebsiella, Proteus, and Pseudomonas were the most frequently cultivated bacteria. Before RT, targeted bacteria were cultivated from 22.2 percent of edentulous patients and 16.6 percent of dentate patients; 30 days after RT, these microorganisms were recovered from 77.8 percent edentulous and 46.8 percent dentate patients. By PCR, these microorganisms were detected from all edentulous patients, 78.1 percent of dentate patients. The presence of Gram-negative enteric roads and fungi was particularly frequent in patients presenting mucositis level III or IV. Modifications in the oral environment due to RT treatment seem to facilitate the colonization of oral cavity by members of family Enterobacteriaceae, genera Enterococcus and Candida.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doenças Negligenciadas
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Radioterapia
/
Procedimentos Cirúrgicos Operatórios
/
Leveduras
/
Técnicas In Vitro
/
Reação em Cadeia da Polimerase
/
Enterobacteriaceae
/
Infecções por Enterobacteriaceae
/
Boca
/
Noma
Tipo de estudo:
Estudo de avaliação
/
Estudo de prevalência
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Braz. j. microbiol
Assunto da revista:
Microbiologia
Ano de publicação:
2011
Tipo de documento:
Artigo
/
Documento de projeto
País de afiliação:
Brasil
/
Nigéria
Instituição/País de afiliação:
Universidade Estadual Paulista/BR
/
Universidade de São Paulo/BR
/
University of Lagos/NG