Prolapso genital: alteraciones del colágeno como factor etiológico / Genital prolapse: alterations of collagen as an etiological factor
Rev. Hosp. Clin. Univ. Chile
; 22(3): 221-229, 2011. tab
Article
em Es
| LILACS
| ID: lil-647607
Biblioteca responsável:
CL36.1
ABSTRACT
The etiological search of pelvic organ prolapse has led to the study of connective tissue that surrounds it directly, called endopelvic fascia. So there have been several studies looking for changes in the main types of collagen existing in this area, trying to describe the changes that they would experience in order to facilitate the prolapse. It has been postulated mainly a decrease in collagen content, thereby reducing the tensile strength of the suspension elements of the pelvic organs and thus descent occurring. However, the literature has been discordant, and published numerous studies that show an increase of collagen in this area, which could be due to a state of pelvic floor repair in patients with various recognized risk factors. Most publications have different biases that preclude a completely valid conclusion. Because of this, still is not clear what changes would experience at the histological level the endopelvic fascia and there is no consensus among different centers. Here is a review of existing literature on this subject with emphasis on different molecular and histological findings of each study and their biases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Colágeno
/
Prolapso Uterino
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
Idioma:
Es
Revista:
Rev. Hosp. Clin. Univ. Chile
Assunto da revista:
MEDICINA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Chile