Effects of aging and physical activity on articular cartilage: a literature review
Braz. j. morphol. sci
; 29(1): 1-17, Jan.-Mar. 2012.
Article
em En
| LILACS
| ID: lil-654231
Biblioteca responsável:
BR734.1
ABSTRACT
The overall aim of this literature review is, by making use of major databases, to introduce the conceptsabout the articular cartilage structure and the effects of aging on articular cartilage. The effects of physicalexercises on those cartilages are also discussed. The most important observations found are cartilage thicknessdecreases gradually with age as well the content of proteoglycans and water, and there is an increase and thecollagen fibrils, which may be associated with the increased rigidity and fragility of the articular cartilage. Whenproperly done, physical activities produce compressive stimuli which enhance the activity of chondrocytesincreasing its nuclear volume density per area, as well as the width of the layers leading to greater resistance tocompression. Another consequence is extracellular matrix hydration resulting in greater mechanical resistanceand elasticity and a consequent increase the number of collagen fibrils which generates greater resistance todeformation and implies less rigidity. These facts reduce the risk of breakdown of cartilage when it is subjectedto high mechanical demand.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Envelhecimento
/
Exercício Físico
/
Cartilagem Articular
Idioma:
En
Revista:
Braz. j. morphol. sci
Assunto da revista:
ANATOMIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil