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Hypovitaminosis D in Children with Hashimoto’s Thyroiditis / Hipovitaminosis D en niños con tiroiditis de Hashimoto
Sönmezgöz, Ergün; Ozer, Samet; Yilmaz, Resul; Önder, Yalçın; Bütün, Ilknur; Bilge, Serap.
Afiliação
  • Sönmezgöz, Ergün; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
  • Ozer, Samet; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
  • Yilmaz, Resul; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
  • Önder, Yalçın; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
  • Bütün, Ilknur; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
  • Bilge, Serap; Gaziosmanpasa University Tokat. School of Medicine. Department of Pediatrics. TR
Rev. méd. Chile ; 144(5): 611-616, mayo 2016. ilus, tab
Artigo em Espanhol | LILACS-Express | LILACS | ID: lil-791049
Biblioteca responsável: CL1.1
ABSTRACT

Background:

Vitamin D deficiency or insufficiency may play a role in the pathogenesis of certain autoimmune diseases.

Aim:

To measure vitamin D levels in children with Hashimoto’s thyroiditis (HT) (either with subclinical or marked hypothyroidism) and in healthy controls. Material and

Methods:

We included 68 children with HT aged 12 ± 4 years (39 females) from a pediatric outpatient clinic and 68 healthy children aged 10 ± 4 years (37 females). Calcium metabolism parameters, thyroid function tests and anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-TG) and 25 hydroxy vitamin D (25OHD) levels were measured.

Results:

Patients were older than controls but well matched by gender distribution. Mean 25OHD levels were significantly lower in HT patients than controls (16.8 ± 9.3 and 24.1 ± 9.4 ng/mL respectively, P < 0.01). Frequency of vitamin D deficiency was 76 and 35% in HT patients and controls, respectively (P < 0.001).

Conclusions:

Vitamin D deficiency is more common in children with HT than healthy controls.
RESUMEN
Antecedentes La deficiencia o insuficiencia de vitamina D puede tener un rol en la patogenia de enfermedades autoinmunes.

Objetivo:

Medir niveles de vitamina D en niños con tiroiditis de Hashimoto (TH) (con hipotiroidismo subclínico o marcado) y en controles sanos. Material y

Métodos:

Estudiamos 68 niños con TH, de 12 ± 4 años (39 mujeres) y 68 controles sanos de 10 ± 4 años (37 mujeres). Se les midió parámetros de metabolismo de calcio, pruebas de función tiroidea, anticuerpos anti peroxidasa y anti tiroglobulina y 25 hidroxi vitamina D (25 OH vit D).

Resultados:

Los pacientes eran mayores que los controles pero la distribución por género era homogénea en ambos grupos. Los niveles de 25 OH vit D en pacientes y controles fueron 16,8 ± 9,3 y 24,1 ± 9,4 ng/mL respectivamente, p < 0,01. La frecuencia de deficiencia de vitamina D fue de 76 y 35% en pacientes y controles, respectivamente.

Conclusiones:

La deficiencia de vitamina D es más común en niños con TH.

Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Espanhol Revista: Rev. méd. Chile Assunto da revista: Medicina Ano de publicação: 2016 Tipo de documento: Artigo País de afiliação: Turquia Instituição/País de afiliação: Gaziosmanpasa University Tokat/TR

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Texto completo: Disponível Coleções: Bases de dados internacionais Base de dados: LILACS Idioma: Espanhol Revista: Rev. méd. Chile Assunto da revista: Medicina Ano de publicação: 2016 Tipo de documento: Artigo País de afiliação: Turquia Instituição/País de afiliação: Gaziosmanpasa University Tokat/TR
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