Localization of PDK-1 mRNA in the brain of developing and adult rats.
Tohoku J Exp Med
; 187(3): 249-55, 1999 Mar.
Article
em En
| MEDLINE
| ID: mdl-10458481
ABSTRACT
Gene expression for 3-phosphoinositide-dependent protein kinase-1 (PDK-1) in developing and adult rat brains was examined by in situ hybridization histochemistry. In embryonic days, the mRNA was evident throughout the entire neuraxis. The expression remained evident throughout the entire gray matters until postnatal day 7, and thereafter it decreased overall in the mantle and ventricular zones except for the cerebellar Purkinje and granule cell layers, the olfactory and hippocampal neuronal layers. The pattern of this gene expression is similar to those of for protein kinase B and class I phosphoinositide 3-kinases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Proteínas Serina-Treonina Quinases
Limite:
Animals
Idioma:
En
Revista:
Tohoku J Exp Med
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Japão