Imaging features of thalassemia.
Eur Radiol
; 9(9): 1804-9, 1999.
Article
em En
| MEDLINE
| ID: mdl-10602954
ABSTRACT
Thalassemia is a kind of chronic, inherited, microcytic anemia characterized by defective hemoglobin synthesis and ineffective erythropoiesis. In all thalassemias clinical features that result from anemia, transfusional, and absorptive iron overload are similar but vary in severity. The radiographic features of beta-thalassemia are due in large part to marrow hyperplasia. Markedly expanded marrow space lead to various skeletal manifestations including spine, skull, facial bones, and ribs. Extramedullary hematopoiesis (ExmH), hemosiderosis, and cholelithiasis are among the non-skeletal manifestations of thalassemia. The skeletal X-ray findings show characteristics of chronic overactivity of the marrow. In this article both skeletal and non-skeletal manifestations of thalassemia are discussed with an overview of X-ray findings, including MRI and CT findings.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talassemia
/
Osso e Ossos
/
Imageamento por Ressonância Magnética
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Turquia