The genetics of the protein 4.1 family: organizers of the membrane and cytoskeleton.
Curr Opin Cell Biol
; 12(2): 229-34, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10712924
ABSTRACT
Protein 4.1 (also called band 4.1 or simply 4.1) was originally identified as an abundant protein of the human erythrocyte, in which it stabilizes the spectrin/actin cytoskeleton. The protein and its relatives have since been found in many cell types of metazoan organisms and they are often concentrated in the nucleus, as well as in cell-cell junctions. They form multimolecular complexes with transmembrane and membrane-associated proteins, and these complexes may be important for both structural stability and signal transduction at sites of cell contact.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Citoesqueleto
/
Neuropeptídeos
/
Proteínas do Citoesqueleto
/
Membrana Eritrocítica
/
Proteínas de Membrana
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Opin Cell Biol
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos