Inhibitory effect of a cyclic urea derivative on rubella virus replication.
Z Naturforsch C J Biosci
; 55(3-4): 292-4, 2000.
Article
em En
| MEDLINE
| ID: mdl-10817222
ABSTRACT
1-(4-Morpholinomethyl)-tetrahydro-2(1H)-pyrimidinone (mopyridone) exhibited a marked activity against rubella virus (Judith and RA27/3 strains), a MIC50 value of 0.9 microM and selectivity ratio of 557.7 been found in the case of Judith strain. These data, in addition to the previous ones about its anti-alphavirus effects suggest the compound to be considered as a broad spectrum inhibitor of togavirus replication.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Pirimidinonas
/
Vírus da Rubéola
/
Replicação Viral
Limite:
Animals
Idioma:
En
Revista:
Z Naturforsch C J Biosci
Ano de publicação:
2000
Tipo de documento:
Article