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Children's exposure assessment: a review of factors influencing Children's exposure, and the data available to characterize and assess that exposure.
Cohen Hubal, E A; Sheldon, L S; Burke, J M; McCurdy, T R; Berry, M R; Rigas, M L; Zartarian, V G; Freeman, N C.
Afiliação
  • Cohen Hubal EA; National Exposure Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA. hubal.elaine@epa.gov
Environ Health Perspect ; 108(6): 475-86, 2000 Jun.
Article em En | MEDLINE | ID: mdl-10856019
ABSTRACT
We review the factors influencing children's exposure to environmental contaminants and the data available to characterize and assess that exposure. Children's activity pattern data requirements are demonstrated in the context of the algorithms used to estimate exposure by inhalation, dermal contact, and ingestion. Currently, data on children's exposures and activities are insufficient to adequately assess multimedia exposures to environmental contaminants. As a result, regulators use a series of default assumptions and exposure factors when conducting exposure assessments. Data to reduce uncertainty in the assumptions and exposure estimates are needed to ensure chemicals are regulated appropriately to protect children's health. To improve the database, advancement in the following general areas of research is required identification of appropriate age/developmental benchmarks for categorizing children in exposure assessment; development and improvement of methods for monitoring children's exposures and activities; collection of activity pattern data for children (especially young children) required to assess exposure by all routes; collection of data on concentrations of environmental contaminants, biomarkers, and transfer coefficients that can be used as inputs to aggregate exposure models.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xenobióticos / Proteção da Criança / Exposição Ambiental Tipo de estudo: Prognostic_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn Idioma: En Revista: Environ Health Perspect Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xenobióticos / Proteção da Criança / Exposição Ambiental Tipo de estudo: Prognostic_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant / Newborn Idioma: En Revista: Environ Health Perspect Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Estados Unidos
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