Post-mortem findings in fetal and neonatal congenital diaphragmatic hernia.
Eur J Pediatr Surg
; 10(2): 96-9, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10877076
ABSTRACT
Analyses of survival data of neonates born with congenital diaphragmatic hernia (CDH) can be misleading. There is a hidden mortality only apparent when fetuses with CDH are included in the analysis. A retrospective review of all post mortems with a diagnosis of CDH in the West of Scotland over a 10-year period was carried out. Congenital anomalies were identified and heart and lung weights were compared with controls (infants dying of non-cardiorespiratory causes). 70 Pm reports were studied. Major congenital anomalies were present in 53% (18/ 47 live born, 19/23 not live born). Neural tube defects, cardiac and chromosomal anomalies were the most common. Antenatal detection rate was 17% in live-born infants. In infants dying within the first week of life lung weights showed severe pulmonary hypoplasia, but heart weights were within the normal range. Detailed antenatal scanning needs to be considered if the detection rate for CDH is to improve in this region.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Fetais
/
Hérnias Diafragmáticas Congênitas
/
Hérnia Diafragmática
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Eur J Pediatr Surg
Assunto da revista:
PEDIATRIA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Reino Unido