Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1.
J Virol
; 74(18): 8726-31, 2000 Sep.
Article
em En
| MEDLINE
| ID: mdl-10954574
ABSTRACT
Human herpesvirus 6 (HHV-6) has been proposed as a potential cofactor in the progression of human immunodeficiency virus type 1 (HIV-1) disease. We used the SCID-hu Thy/Liv mouse model to evaluate the in vivo interactions between HHV-6 and HIV-1. Our results demonstrate that HHV-6 and HIV-1 can simultaneously replicate in the human thymus in vivo. In this model, however, the presence of one virus appears not to modify the replication or cytopathicity of the other.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
HIV-1
/
Herpesvirus Humano 6
/
Infecções por Herpesviridae
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Virol
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Itália