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Application of acoustic emission to the monitoring and end point determination of a high shear granulation process.
Whitaker, M; Baker, G R; Westrup, J; Goulding, P A; Rudd, D R; Belchamber, R M; Collins, M P.
Afiliação
  • Whitaker M; Pharmaceutical Development, Glaxo Wellcome Research and Development, Park Road, Ware, Hertfordshire, SG12 0DP, UK. mw2541@glaxowellcome.co.uk
Int J Pharm ; 205(1-2): 79-92, 2000 Sep 15.
Article em En | MEDLINE | ID: mdl-11000544
ABSTRACT
The application of a novel monitoring technique, based on the use of acoustic emissions, is reported for a model high shear granulation process. It has been demonstrated that this technique is capable of monitoring changes in physical properties of powder material during granulation (particle size, flow properties and compression properties). The technique is non-invasive, sensitive and relatively inexpensive.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pós / Comprimidos / Acústica Idioma: En Revista: Int J Pharm Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Reino Unido
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pós / Comprimidos / Acústica Idioma: En Revista: Int J Pharm Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Reino Unido