[Chloroquine-induced drug hypersensitivity alveolitis]. / Chloroquin-induzierte arzneimitteltoxische Alveolitis.
Pneumologie
; 54(9): 395-7, 2000 Sep.
Article
em De
| MEDLINE
| ID: mdl-11072724
This case history presents a 41-years-old man with chronic discoid erythematosus who was treated with chloroquine. After 2 weeks of treatment he developed dyspnea, purulent sputum, high fever, diffuse papular rash, and diffuse peripheral homogeneous infiltrates on chest x-ray. Rapid recovery occurred after discontinuing chloroquine. Subsequent peroral provocation with chloroquine caused symptoms suggestive of hypersensitivity pneumonitis. Analysis of bronchoalveolar lavage fluid showed eosinophilia and a reduced CD4/CD8 ratio. Although treatment with chloroquine is often complicated by side effects, in a literature search we could not find any report on acute pneumonitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lúpus Eritematoso Discoide
/
Cloroquina
/
Antirreumáticos
/
Hipersensibilidade a Drogas
/
Alveolite Alérgica Extrínseca
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
De
Revista:
Pneumologie
Ano de publicação:
2000
Tipo de documento:
Article
País de publicação:
Alemanha