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[Chloroquine-induced drug hypersensitivity alveolitis]. / Chloroquin-induzierte arzneimitteltoxische Alveolitis.
Mitja, K; Izidor, K; Music, E.
Afiliação
  • Mitja K; Universitätskrankenhaus für Pneumologie und Allergologie, Golnik/Slovenia.
Pneumologie ; 54(9): 395-7, 2000 Sep.
Article em De | MEDLINE | ID: mdl-11072724
This case history presents a 41-years-old man with chronic discoid erythematosus who was treated with chloroquine. After 2 weeks of treatment he developed dyspnea, purulent sputum, high fever, diffuse papular rash, and diffuse peripheral homogeneous infiltrates on chest x-ray. Rapid recovery occurred after discontinuing chloroquine. Subsequent peroral provocation with chloroquine caused symptoms suggestive of hypersensitivity pneumonitis. Analysis of bronchoalveolar lavage fluid showed eosinophilia and a reduced CD4/CD8 ratio. Although treatment with chloroquine is often complicated by side effects, in a literature search we could not find any report on acute pneumonitis.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lúpus Eritematoso Discoide / Cloroquina / Antirreumáticos / Hipersensibilidade a Drogas / Alveolite Alérgica Extrínseca Tipo de estudo: Diagnostic_studies Limite: Adult / Humans / Male Idioma: De Revista: Pneumologie Ano de publicação: 2000 Tipo de documento: Article País de publicação: Alemanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lúpus Eritematoso Discoide / Cloroquina / Antirreumáticos / Hipersensibilidade a Drogas / Alveolite Alérgica Extrínseca Tipo de estudo: Diagnostic_studies Limite: Adult / Humans / Male Idioma: De Revista: Pneumologie Ano de publicação: 2000 Tipo de documento: Article País de publicação: Alemanha