Naltrexone: effects on motor function, speech, and activities of daily living in a patient with traumatic brain injury.
Brain Inj
; 14(10): 933-42, 2000 Oct.
Article
em En
| MEDLINE
| ID: mdl-11076138
ABSTRACT
Evidence from many studies has suggested that endogenous opioid peptides participate in a number of pathophysiological responses to brain injury. This provides the rationale for the use of opioid antagonists for the enhancement of neural recovery after brain injury. A case is presented of an 18-year-old male who had loss of consciousness for 1 month after a severe brain injury. Three months of intensive rehabilitative therapies did not change his functional status. A trial of naltrexone was given while his performance in mobility, speech and overall Functional Independence Measure (FIM) scores were monitored. Results indicate an accelerated improvement in functional status and statistically improved FIM score.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fala
/
Lesões Encefálicas
/
Destreza Motora
/
Naltrexona
/
Antagonistas de Entorpecentes
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Brain Inj
Assunto da revista:
CEREBRO
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Estados Unidos