[Reactive hemaphagocytic syndrome in a patient with midline NK-cell lymphoma]. / Syndrome d'activation macrophagique au cours d'un lymphome NK centro-facial.

ABSTRACT

Different etiologies have been shown to underly lethal midline granuloma. Evidence of natural killer cell lymphoma is obtained by immunolabeling and molecular biology studies. The tumor has a characteristic immunophenotype and genotype. This clinicopathological entity is highly associated with Epstein-Barr virus (EBV). We present the case of a patient with EBV associated with nasal-type natural-killer cell lymphoma and a coexisting hemophagocytic syndrome.