Effect of medroxyprogesterone acetate plus estradiol on endothelium-dependent vasodilation in postmenopausal women.
Am J Cardiol
; 87(2): 238-40, A9, 2001 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-11152852
ABSTRACT
The addition of medroxyprogesterone acetate (MPA) is widely accepted to remove the endometrial-cancerogenic effect of estrogen replacement therapy in postmenopausal women. To evaluate the effect of MPA on endothelial function, we measured flow-mediated vasodilation of brachial arteries after transient occlusion in a randomized, double-blind, placebo-controlled study; we concluded that the addition of MPA attenuates the favorable effects of estradiol on endothelium-dependent vasodilation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasodilatação
/
Endotélio Vascular
/
Terapia de Reposição de Estrogênios
/
Congêneres da Progesterona
/
Estradiol
/
Medroxiprogesterona
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
Idioma:
En
Revista:
Am J Cardiol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Japão