[Midodrine (Gutron) prescription practice at a University Hospital Center]. / Etude des pratiques de prescriptions de midodrine (Gutron) dans un Centre Hospitalier Universitaire.
Therapie
; 55(5): 613-7, 2000.
Article
em Fr
| MEDLINE
| ID: mdl-11201976
ABSTRACT
A historical study of the prescription of midodrine was carried out at the university hospital of Toulouse (France) between 1994 and 1998. The aim was to compare the observed prescriptions and the ideal prescriptions in accordance with the Summary of Product Characteristics (SPC). The analysis of 97 consecutive medical reports found discrepancies in prescription concerning the non-respect of contraindications and of potentially hazardous drug associations. Fifty-four (55.7 per cent) patients would have been excluded from prescription if the physicians had strictly respected the SPC. The inappropriate prescription of midodrine was associated with an increase in adverse drug reactions (ADRs). ADRs occurred in 34.0 per cent of cases overall and required drug discontinuation in 15.5 per cent.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Prescrições de Medicamentos
/
Vasoconstritores
/
Pró-Fármacos
/
Revisão de Uso de Medicamentos
/
Agonistas alfa-Adrenérgicos
/
Midodrina
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
Fr
Revista:
Therapie
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
França