[Androgens and laryngeal cancer]. / Androgeny a rak krtani.

ABSTRACT

The article concerns relations between larynx cancer and androgenic activity in men. Up till now the role of androgens in laryngeal carcinogenesis has not been established. Authors point out to andropenia (gonadal and supracortical) in elderly males and its influence on larynx cancer occurrence in the course of aging. Results of androgen receptor studies in unchanged and neoplastic tissue of the vocal organ are described. There is presented data on serum androgen concentrations in healthy men and patients with laryngeal neoplasms. The necessity of further studies of the larynx cancer's hormone-dependence is underlined.