Pancreatic dysfunction in severe obesity.
Arch Dis Child
; 84(3): 261-2, 2001 Mar.
Article
em En
| MEDLINE
| ID: mdl-11207179
ABSTRACT
AIMS:
To investigate pancreatic function in children attending an obesity clinic.METHODS:
Thirty six children (of which 34 were white) with severe obesity of prepubertal onset (body mass index more than +2 SDS) were reviewed clinically and dysmorphologically, with assessment of pancreatic function.RESULTS:
Eight had dysmorphic features and 13 had learning difficulties. Four of 17 prepubertal children had hyperinsulinaemia and seven had hyperproinsulinaemia. All 19 pubertal children had hyperinsulinaemia, 14 had hyperproinsulinaemia, and one had type II diabetes.CONCLUSIONS:
Metabolic abnormalities predictive of type II diabetes occur in severely obese white children.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pâncreas
/
Obesidade Mórbida
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arch Dis Child
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Reino Unido