Multiple mobile promoter regions for the rare carbapenem resistance gene of Bacteroides fragilis.
J Bacteriol
; 183(11): 3531-5, 2001 Jun.
Article
em En
| MEDLINE
| ID: mdl-11344163
ABSTRACT
Two novel insertion sequences (IS), IS1187 and IS1188, are described upstream from the carbapenem resistance gene cfiA in strains of Bacteroides fragilis. Mapping, with the RACE procedure, of transcription start sites of cfiA in these and two other previously reported IS showed that transcription of this rarely encountered gene is initiated close to a variety of B. fragilis consensus promoter sequences, as recently defined (D. P. Bayley, E. R. Rocha, and C. J. Smith, FEMS Microbiol. Lett. 193149-154, 2000). In the cases of IS1186 and IS1188, these sequences overlap with putative Esigma(70) promoter sequences, while in IS942 and IS1187 such sequences can be observed either upstream or downstream of the B. fragilis promoters.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Bacteroides fragilis
/
Beta-Lactamases
/
Elementos de DNA Transponíveis
/
Carbapenêmicos
/
Regiões Promotoras Genéticas
Idioma:
En
Revista:
J Bacteriol
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
França