Acquired neuromyotonia and peripheral neuropathy in a patient with Hodgkin's disease.
Muscle Nerve
; 24(6): 834-8, 2001 Jun.
Article
em En
| MEDLINE
| ID: mdl-11360270
ABSTRACT
Acquired neuromyotonia is characterized by hyperexcitability of motor nerves resulting in continuous muscle fiber activity. It occurs most often as a paraneoplastic syndrome in patients with cancers of the immune system. Antibodies against voltage-gated potassium channels (VGKCs) have been detected in some patients. Peripheral neuropathy is sometimes present. We report on a patient with Hodgkin's lymphoma in complete remission who developed paresthesias followed by neuromyotonia with bulbar involvement. Peripheral sensorimotor neuropathy was diagnosed electrophysiologically and evidence of axonal degeneration and demyelination was detected by sural nerve biopsy. The patient's complaints, including dysarthria, improved after carbamazepine treatment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nervos Periféricos
/
Doença de Hodgkin
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Doenças do Sistema Nervoso Periférico
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Síndrome de Isaacs
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Muscle Nerve
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Áustria