Differential effects of fasting and nicotinic acid on various enzymatic activities of the 9,000 g fraction of the perfused rat liver.
Pharmacology
; 13(3): 212-8, 1975.
Article
em En
| MEDLINE
| ID: mdl-1153505
ABSTRACT
Perfused livers obtained from rats fasted for 24 or 48h show a marked impairment of the N-demethylation (substrate aminopyrine) without major changes of the O-demethylation (p-nitro anisol) and hydroxylation (aniline). The infusion with nicotinic acid restored N-demethylation but it inhibited O-demethylation and hydroxylation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxirredutases
/
Microssomos Hepáticos
/
Anilina Hidroxilase
/
Jejum
/
Aminopirina N-Desmetilase
/
Oxigenases de Função Mista
/
Ácidos Nicotínicos
/
Nitroanisol O-Desmetilase
Limite:
Animals
Idioma:
En
Revista:
Pharmacology
Ano de publicação:
1975
Tipo de documento:
Article