Is blood homocysteine elevated in migraine?
Headache
; 41(8): 779-81, 2001 Sep.
Article
em En
| MEDLINE
| ID: mdl-11576202
ABSTRACT
OBJECTIVE:
To determine total serum homocysteine levels in a large group of patients with migraine with and without aura.BACKGROUND:
Hypercoagulable state is a known risk factor for stroke in the young. The existence of a hypercoagulable state has been postulated in migraine and homocysteinemia with young-onset stroke. To the best of our knowledge, blood homocysteine has not been studied in a significant number of patients with various forms of migraine.METHODS:
Total serum homocysteine was measured with high-performance liquid chromatography in 78 patients with migraine and in 126 age- and sex-matched healthy volunteers.RESULTS:
Seventy-eight patients aged 18 to 65 years were studied 22 with migraine with aura and 56 with migraine without aura. Only 1 man had significantly elevated blood homocysteine (38.6 micromol/L), while another had a borderline elevation (15.8 micromol/L) (reference value for both sexes in our laboratory is 4 to 14 micromol/L). Both patients suffered from migraine without aura.CONCLUSIONS:
Blood homocysteine is not elevated in migraine.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Homocisteína
/
Transtornos de Enxaqueca
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Headache
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Israel